Pankaj Baral, Assistant Professor
Contact information
239C Chalmers Hall
(785) 532-6332
baral@ksu.edu
Lab website: https://www.barallab.com
Education
Ph.D. 2013, Mahidol University, Thailand, Microbiology and Immunology
Area(s) of Specialization
Neuroimmunology, Innate immunity, Airway inflammation, Infectious disease, Host-pathogen interactions.
Research Focus
Selected Publications
Zhang B, Ma S, Rachmin I, He M, Baral P, Choi S, Goncalves W, Shwartz Y, Fast EV, Su Y, Zon LI, Regev A, Buenrostro JD, Cunha TM, Chiu IM, Fisher DE, Hsu Y. 2020. Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells, Nature, 577(7792):676-681.
Lai NY, Musser MA*, Pinho-Ribeiro FA*, Baral P*, Jacobson A*, Ma P, Potts DE, Chen Z, Paik D, Soualhi S, Yan Y, Misra A, Goldstein K, Lagomarsino VN, Nordstrom A, Sivanathan KN, Wallrapp A, Kuchroo VK, Nowarski R, Starnbach MN, Shi H, Surana NK, An D, Wu C, Huh JR, Rao M, Chiu IM. 2020. Gut-innervating nociceptor neurons regulate Peyer's patch microfold cells and SFB levels to mediate Salmonella host defense, Cell 180, 33–49.
Baral P, Udit S, Chiu IM. Pain and immunity: implications for host defence. 2019. Nature Reviews Immunology 19(7):433-447.
Paudel S, Baral P, Ghimire L, Bergeron S, Jin L, DeCorte JA, Le JT, Cai S, Jeyaseelan S. 2019. CXCL1 regulates neutrophil homeostasis in pneumonia-derived sepsis caused by Streptococcus pneumoniae serotype 3. Blood 133(12):1335-1345.
Baral P, Umans BD, Li L, Wallrapp A, Bist M, Kirschbaum T, Wei Y, Zhou Y, Kuchroo VK, Burkett PR, Yipp BG, Liberles SD, Chiu IM. 2018. Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia. Nature Medicine (4):417-426.
Blake KJ, Baral P, Voisin T, Lubkin A, Pinho-Ribeiro FA, Adams KL, Roberson DP, Ma YC, Otto M, Woolf CJ, Torres VJ, Chiu IM. 2018. Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314. Nature Communications 9(1):37.
Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VK. 2017. The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation. Nature 549(7672):351-356.
Baral P, Mills K, Pinho-Ribeiro FA, Chiu IM. 2016. Pain and Itch: Beneficial or Harmful to Antimicrobial Defense? Cell Host Microbe, 19(6):755-9.
Baral P, Batra S, Zemans RL, Downey GP, Jeyaseelan S. 2014. Divergent functions of Toll-like receptors during bacterial lung infections. American Journal of Respiratory and Critical Care Medicine 190(7):722-32.
Baral P, Utaisincharoen P. 2013. Sterile α and armadillo motif containing protein inhibits the TRIF-dependent downregulation of signal regulatory protein α to interfere with intracellular bacterial elimination in Burkholderia pseudomallei-infected mouse macrophages. Infection and Immunity 81(9):3463M71.
Baral P, Utaisincharoen P. 2012 Involvement of signal regulatory protein, a negative regulator of Toll-like receptor signaling, in impairing MyD88Mindependent pathway and intracellular killing of Burkholderia pseudomallei-infected mouse macrophages, Infection and Immunity 80(12):4223M31
For a complete list of publications visit my Google Scholar page